IGF-1 LR3 | 1mg
$44.99
IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3) is a synthetic peptide analog often studied for its potential role in supporting cellular growth, recovery, and metabolic research. This 1mg vial contains high-purity IGF-1 LR3, designed exclusively for laboratory and scientific research applications.
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IGF-1 LR3 (Insulin-Like Growth Factor 1, Long Arg3) is a synthetic analog of human IGF-1, a naturally occurring growth factor closely related to insulin. IGF-1 is central to cell growth, development, and survival, influencing nearly every tissue in the body. The LR3 modification extends the peptide chain to 83 amino acids and substitutes arginine at position 3, dramatically reducing its binding to IGF-binding proteins (IGFBPs). This results in increased bioavailability and prolonged activity compared to native IGF-1, making LR3 especially valuable in laboratory studies requiring stable signaling.
Researchers utilize IGF-1 LR3 in projects focused on:
-
Cellular proliferation and differentiation – understanding how growth factor signaling drives tissue development and repair.
-
Muscle physiology and regeneration – mapping pathways of hypertrophy, satellite cell activation, and recovery after injury.
-
Metabolic regulation – exploring insulin-like effects on glucose uptake, nutrient partitioning, and mitochondrial health.
-
Signal transduction – studying activation of the PI3K/Akt and MAPK/ERK pathways, both of which are central to cell growth and survival.
-
Aging and longevity – examining how IGF-1 signaling interacts with pathways of senescence and lifespan regulation.
Each vial contains high-purity IGF-1 LR3, formulated for stability and reproducibility in laboratory settings. Its extended half-life and reduced IGFBP binding profile make it an exceptional research tool for studying both short-term and long-term effects of growth factor activity.
This product is intended strictly for laboratory and scientific research only—not for human consumption or therapeutic use.
Technical Information
-
CAS Number: 946870-92-4
-
Sequence Length: 83 amino acids (extended from native 70 aa IGF-1)
-
Molecular Weight (MW): ~9,111 g/mol
-
Synonyms: Insulin-Like Growth Factor 1 Long R3, IGF-1 LR3, LR3 IGF-1
-
Modification Details: Arg substitution at position 3 (Arg3) and extended N-terminal peptide sequence to reduce IGFBP binding
| Size |
20mg ,30mg |
|---|
| CAS Number | 946870-92-4 |
|---|---|
| PubChem CID | N/A |
| Molecular Weight | 9,117.5 g/mol |
| Molecular Formula | C400H625N111O115S9 |
| Synonyms | Long R3 IGF-I, Insulin-like Growth Factor-I Long Arg3, LR3-IGF-1 |
| Storage (Lyophilized) | Store in a cool, dry, and dark place. Refrigerate after reconstitution. |
Storage Instructions:
- Lyophilized (Powder): Store at -20°C in a cool, dry, and dark place.
- After Reconstitution: Refrigerate at 2-8°C and use within 14-21 days.
- Long-Term Storage: Freeze at -20°C in sterile aliquots. Avoid repeated freeze-thaw cycles.
- Handling: Use aseptic conditions in a laboratory setting.
IGF-1 LR3 (Insulin-Like Growth Factor 1, Long Arg3) is a synthetic analog of human IGF-1, a naturally occurring growth factor closely related to insulin. IGF-1 is central to cell growth, development, and survival, influencing nearly every tissue in the body. The LR3 modification extends the peptide chain to 83 amino acids and substitutes arginine at position 3, dramatically reducing its binding to IGF-binding proteins (IGFBPs). This results in increased bioavailability and prolonged activity compared to native IGF-1, making LR3 especially valuable in laboratory studies requiring stable signaling.
Researchers utilize IGF-1 LR3 in projects focused on:
-
Cellular proliferation and differentiation – understanding how growth factor signaling drives tissue development and repair.
-
Muscle physiology and regeneration – mapping pathways of hypertrophy, satellite cell activation, and recovery after injury.
-
Metabolic regulation – exploring insulin-like effects on glucose uptake, nutrient partitioning, and mitochondrial health.
-
Signal transduction – studying activation of the PI3K/Akt and MAPK/ERK pathways, both of which are central to cell growth and survival.
-
Aging and longevity – examining how IGF-1 signaling interacts with pathways of senescence and lifespan regulation.
Each vial contains high-purity IGF-1 LR3, formulated for stability and reproducibility in laboratory settings. Its extended half-life and reduced IGFBP binding profile make it an exceptional research tool for studying both short-term and long-term effects of growth factor activity.
This product is intended strictly for laboratory and scientific research only—not for human consumption or therapeutic use.
Technical Information
-
CAS Number: 946870-92-4
-
Sequence Length: 83 amino acids (extended from native 70 aa IGF-1)
-
Molecular Weight (MW): ~9,111 g/mol
-
Synonyms: Insulin-Like Growth Factor 1 Long R3, IGF-1 LR3, LR3 IGF-1
-
Modification Details: Arg substitution at position 3 (Arg3) and extended N-terminal peptide sequence to reduce IGFBP binding
| CAS Number | 946870-92-4 |
|---|---|
| PubChem CID | N/A |
| Molecular Weight | 9,117.5 g/mol |
| Molecular Formula | C400H625N111O115S9 |
| Synonyms | Long R3 IGF-I, Insulin-like Growth Factor-I Long Arg3, LR3-IGF-1 |
| Storage (Lyophilized) | Store in a cool, dry, and dark place. Refrigerate after reconstitution. |
Storage Instructions:
- Lyophilized (Powder): Store at -20°C in a cool, dry, and dark place.
- After Reconstitution: Refrigerate at 2-8°C and use within 14-21 days.
- Long-Term Storage: Freeze at -20°C in sterile aliquots. Avoid repeated freeze-thaw cycles.
- Handling: Use aseptic conditions in a laboratory setting.
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